What is the Main Cause Of Parkinson’s Disease?

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What is the Main Cause Of Parkinson’s Disease?
Parkinson's disease is a neurodegenerative disorder that affects millions of people worldwide. It causes a progressive decline in motor function which significantly impacts the quality of life of those diagnosed.

In Canada, 1 in every 500 people is affected by Parkinson’s disease. It is essential to understand the main cause of Parkinson’s disease to develop effective treatments and potentially even find a cure. In this article, we will look deeper into the major causes of Parkinson’s disease, its symptoms, and contributing factors. 


Causes and Contributing Factors:


Parkinson’s disease is characterized by the gradual breakdown or death of certain neurons in the brain. The loss of these neurons which are responsible for producing dopamine, contributes to many of the symptoms associated with Parkinson’s. When dopamine levels decrease, it disrupts normal brain activity leading to movement difficulties and other Parkinson’s symptoms.


The exact cause of Parkinson’s disease is still unknown, but several factors are believed to play a role. These factors include:


  • Genetic Factors:


Genetics are believed to play a role in the development of Parkinson’s disease. Research has shown that specific genes can influence an individual’s susceptibility to the disease. By analyzing these genes, scientists have gained insights into the biological mechanisms behind Parkinson’s disease.


  • Environmental Factors:


Although genetics play a role in the development of Parkinson’s disease, there are also environmental factors that can contribute to its onset. Exposure to certain toxins and chemicals like pesticides and industrial solvents has been associated with an increased risk. By exploring these environmental factors, we can gain a better understanding of the complex nature of the disease.


  • Oxidative Stress and Mitochondrial Dysfunction:


Parkinson’s disease has been linked to oxidative stress, which is caused by an imbalance between harmful free radicals and the body’s natural antioxidant defenses. The disease can also be caused by dysfunction in the mitochondria, which are responsible for the energy production in our cells. By understanding these processes, we can gain insights into potential therapeutic targets to treat the disease.


  • Protein Aggregation and Lewy Bodies:


The accumulation of malfunctioning proteins, specifically alpha-synuclein, leads to the formation of abnormal protein clumps called Lewy bodies. These protein aggregates disrupt normal brain function, contributing to the symptoms of Parkinson’s Disease. Understanding the mechanisms behind protein aggregation is crucial for developing interventions that can prevent or reverse this process.


  • The Role of Dopamine:


Dopamine, which is a neurotransmitter responsible for motor control, plays a crucial role in Parkinson’s Disease. The characteristic motor symptoms of the disease are caused by a deficiency of dopamine in specific parts of the brain. Studying the role of dopamine can aid in comprehending how the disease progresses and exploring methods to regulate dopamine levels.


  • Neuroinflammation:


Recent research suggests that neuroinflammation, the activation of the brain’s immune response, plays a significant role in Parkinson’s Disease. Chronic inflammation can contribute to neuronal damage and accelerate disease progression. Identifying potential therapeutic targets to mitigate neuroinflammation holds promise for developing new treatments for the disease.


Are your loved ones suffering from Parkinson’s disease? ConsidraCare provides specialized Parkinson’s Care with compassion to improve the quality of life for those affected. Contact Us today!



What is the Main Cause Of Parkinson’s Disease?


Symptoms of Parkinson’s:


Symptoms of Parkinson’s Disease can vary among individuals and some may not even initially notice mild symptoms. Typically, symptoms begin on one side of the body and continue to affect that side more significantly than the other. As the disease progresses, it often affects the limbs on both sides


Parkinson’s disease commonly presents with motor symptoms which include:

  • Tremors
  • Rigidity
  • Bradykinesia (slowed movement)


Apart from motor symptoms, individuals may also experience non-motor symptoms such as:

  • Cognitive impairment
  • Depression
  • Sleep disturbances




Parkinson’s Disease is a brain disorder that currently has no known cause or prevention. However, some studies suggest that making certain lifestyle choices could lower the risk of developing it. Regular aerobic exercise like running or swimming may help protect the brain from damage. Additionally, drinking beverages like coffee, tea, or cola that contain caffeine may also reduce the likelihood of developing Parkinson’s. Green tea may have a similar effect. However, these findings are not conclusive and more research is needed to confirm them. 




Parkinson’s disease is a complex neurodegenerative disorder with a significant impact on individuals’ lives. With approximately 6600 new cases diagnosed in Canada each year, it is crucial to continue researching and understanding the causes and contributing factors of the disease. This knowledge will aid in the development of effective treatments and potentially finding a cure. 


Want to learn more?


Reach us at wecare@considracare.com, or call us at 1-855-410-7971, and we will be happy to assist. Discover more tips in our information booklets or on our resources page.




1. What is the number one cause of Parkinson’s disease?


The exact cause of Parkinson’s disease is unknown, but a combination of genetic and environmental factors is believed to contribute.


2. Can you live normal with Parkinson?


While there’s no cure, many Parkinson’s patients can lead relatively normal lives with proper medication, therapy, and support.


3. What should Parkinson’s patients avoid?


Parkinson’s patients may consider avoiding excessive caffeine and high-protein diets, as they can interfere with medication absorption.


4. What is the first thing to do if you have Parkinson’s disease?


If diagnosed with Parkinson’s disease, consult a neurologist for personalized treatment and management plans.


5. Can stress cause Parkinson’s disease?


There’s no direct evidence that stress causes Parkinson’s disease, but managing stress can positively impact overall well-being for those with the condition.

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